To send an HTML email using SMTP in PHP, you first need to create an HTML email message using the proper HTML tags for formatting. Next, you will need to set up an SMTP connection using the PHPMailer library or built-in PHP functions like mail().You will need to specify the SMTP server address, port, username, password, and other SMTP settings. Then, you can create an instance of the PHPMailer class and set the necessary email headers like From, To, Subject, and MIME type.